When Hime was a child, her family's heirloom vase for sealing ghosts (evil spirits) was absorbed into her breasts in a minor accident. This transformed her into a big-breasted woman, and she became a ghost hunter who can absorb more ghosts. As an adult, she took the suction gun attached to her chest and started a company called Ghost Pitters with her partner, the one-goggle-wearing Fukuro, and began to exterminate ghosts. The two are asked to exterminate ghosts one after another, including Satako, the Slit-Mouthed Woman, and Hanako-san in the Toilet, but can they solve this difficult problem?