After missing a week of school right at the start of the new school year due to a mysterious fever, and trying to hide his isolation behind a reading addict persona, Yuuhi Takamiya was in a state of grief! His cry of sorrow "I want friends!" was met with a response from Nano, an alien from the Pokoton planet. She came from outer space to conduct some (aggressive) marketing, and... thanks to her demo product, Yuuhi's high school life will never be the same. A cute and exciting slapstick comedy on a cosmic scale is about to begin!